---

In this study 30 healthy and mature samples of Litopenaeus vannamei and 3o infected samples with white spot virus with mean length of 8±1cm and mean weight of 30±5gr were caught from a farm. After studying morphological parameters, samples were fixed and prepared through usual histological methods and studied under light microscope. In microscopic study of sections different kind of hepatopancreatic cells including reactive-storing, secular, embryonic, entric and myoepithelial cells were determined. Also size and shape of tubules and cells were studied. Because of cell immunity and activity the vacuolated cells of hepatopancreas were more than of normal cells. Hepatopancreas cells were major and abnormal. The nucleous of infected cells were major and the nucleolous were destroyed and inclusion bodies were seen in the cytoplasm of the hepatopancreas cells.Also bacterial infection was seen in cells of hepatopancreas.

---

The present study has been done to a determination of heavy metals chromium (Cr), lead (Pb), zinc (Zn), Cadmium (Cd), Iron (Fe), and nickle (Ni) residuals in Chabahar Bay's Pharaoh Cuttlefish (Sepia pharaonis) comparing to global guidelines. Therefore, 30 numbers of captured Sepia pharaonis by trawling from January to April 2018 have prepared from Chabahar port. Then, after the chemical digestion of the muscle and hepatopancreas samples by nitric acid and perchloric acid, the elements have been measured by atomic emission spectroscopy. Results showed that the minimum of accumulated metals was Cd (muscle), and the maximum was Fe (hepatopancreas) equal to 0.028 (±0.004) and 7.83 (±0.83) µg.g^-1 dry body weight. There was a significant difference between the concentration of Cr and Ni (P< 0.05). Also Cr, Pb, Zn, Cd, Fe, and Ni of the muscle were placed in the allowed standards range of FAO and WHO. Therefore, the muscle of Chabahar Bay's Sepia pharaonis was within the standard range of edible products in terms of the measured trace metals accumulation.