Prospects for the Use of Multifunctional Polymeric Nanoparticles in the Simultaneous Delivery of Vaccines and Immunostimulants in Aquatic Animals

Mobarhan fard, Alireza

Volume 15, Issue 2 (Summer 2023) 3 2023, 15(2): 1-9 | Back to browse issues page

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Mobarhan fard A. Prospects for the Use of Multifunctional Polymeric Nanoparticles in the Simultaneous Delivery of Vaccines and Immunostimulants in Aquatic Animals. 3 2023; 15 (2) :1-9
URL: http://jmb.ahvaz.iau.ir/article-1-1064-en.html

Prospects for the Use of Multifunctional Polymeric Nanoparticles in the Simultaneous Delivery of Vaccines and Immunostimulants in Aquatic Animals

Alireza Mobarhan fard

Department of Fisheries, Faculty of Veterinary Medicine and Agriculture, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.

Abstract: (389 Views)

Targeted delivery of vaccines and immunostimulants in aquaculture has emerged as a critical strategy to enhance fish health and reduce mortality associated with infectious diseases. In this context, the application of multifunctional polymeric nanoparticles (PNPs) as drug and vaccine delivery systems offers promising advancements. These nanoparticles are capable of co-loading multiple bioactive agents, exhibit stability in aquatic environments, and allow for controlled, stimulus-responsive release. Additionally, the biodegradability and biocompatibility of the employed polymers minimize the risk of bioaccumulation and toxicity. This article reviews the physicochemical properties of multifunctional PNPs and explores their innovative applications in the simultaneous delivery of vaccines and immune-enhancing compounds in various farmed fish species. Moreover, the article addresses technical challenges, environmental limitations, and future perspectives related to the development and implementation of these systems. Based on both experimental findings and comprehensive literature review, this study provides a scientific framework for the broader application of nanotechnology in aquatic disease management and fish immunoprophylaxis.

Keywords: Polymeric nanoparticles, Targeted delivery, Fish vaccines, Immunostimulants, Nanotechnology, Aquaculture.

Full-Text [PDF 403 kb] (265 Downloads)

Type of Study: case report | Subject: Fisheries
Received: 2023/04/4 | Accepted: 2023/06/24 | Published: 2023/06/24